Acetyl Octapeptide-3 CAS 868844-74-0

Acetyl Octapeptide-3 CAS 868844-74-0

Acetyl Octapeptide-3 (CAS 868844-74-0), often marketed as Snap-8, is a cutting-edge anti-aging peptide designed to mimic the effects of Botox® in a safe, topical form. It reduces muscle contraction at the skin level, softening expression lines and wrinkles — especially around the forehead, eyes, and mouth. With proven stability in cosmetic formulations, Acetyl Octapeptide-3 has become a star ingredient in premium serums and creams.

 

what's  Acetyl Octapeptide-3?

 

Acetyl Octapeptide-3 (SNAP-8®) cas 868844-74-0 is a highly effective cosmetic peptide designed for anti-wrinkle and anti-aging skincare formulations. As an advanced derivative of Acetyl Hexapeptide-8, it provides enhanced modulation of facial muscle contractions, helping to reduce the depth and appearance of expression lines over time.

Widely used in serums, eye creams, and premium anti-aging formulations, Acetyl Octapeptide-3 is valued by cosmetic brands for its non-invasive, topical approach to wrinkle reduction.

 

Technical Specification

Parameter Specification
Appearance White to off-white powder
Peptide Content ≥ 98% (HPLC)
Water Solubility Soluble in water
Molecular Formula C₄₀H₇₂N₁₆O₁₄
Molecular Weight 904.1 g/mol
pH (1% solution) 4.5 – 6.5
Moisture Content ≤ 5%
Loss on Drying ≤ 5%
Heavy Metals (Pb, As, Hg, Cd) ≤ 10 ppm
Microbial Limits Total Plate Count ≤ 1000 CFU/gYeast & Mold ≤ 100 CFU/gE. coli: NegativeSalmonella: Negative
Storage Store in a cool, dry place, away from light
Shelf Life 24 months (unopened, at 2–8°C)

 

868844-74-0 mol

 

Acetyl Octapeptide-3  benifits & Applications

 

Benefits

  • Reduces dynamic expression wrinkles (forehead, crow's feet, frown lines)
  • Enhances skin smoothness and youthful appearance
  • Non-invasive, reversible alternative to injectable treatments
  • Compatible with creams, serums, and eye-area products
  • Supports synergistic multi-peptide anti-aging formulations

 

Acetyl Octapeptide-3 is used in:

  • Anti-wrinkle serums and facial creams
  • Eye creams and eye contour products
  • Premium skincare formulations

 

 Mechanism of Action 

 

Acetyl Octapeptide-3 works by modulating the SNARE complex, which regulates neurotransmitter release at the neuromuscular junction. By partially inhibiting acetylcholine release, it reduces micro-muscle contractions beneath the skin. This leads to a visible relaxation of expression lines, providing a smoother skin surface without affecting natural facial expressions.

 

Acetyl Octapeptide-3
 Side Effects

 

 

Common Side Effects

  • Slight skin redness or irritation (rare)
  • Temporary tingling or warming sensation
  • Mild dryness or tightness in sensitive skin

Rare Side Effects

  • Localized rash or itching
  • Increased sensitivity in very reactive skin types

Safety Notes

  • Effects are localized and reversible; no systemic absorption
  • Non-invasive, unlike injectable wrinkle treatments
  • Safe for daily cosmetic use at typical concentrations (0.002%–0.05%)

 

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Comparison: Acetyl Octapeptide-3 vs Acetyl Hexapeptide-8 vs Pentapeptide-18

 

 

Feature Acetyl Octapeptide-3 (SNAP-8®) Acetyl Hexapeptide-8 Argireline®) Pentapeptide-18 (Leuphasyl®)
Peptide Length Octapeptide Hexapeptide Pentapeptide
Primary Function Reduces dynamic wrinkles Reduces dynamic wrinkles Muscle relaxation
Mechanism SNARE complex modulation SNARE complex inhibition Neuromuscular signaling modulation
Application Topical (creams, serums) Topical Topical
Onset Gradual (2–4 weeks) Gradual Gradual
Suitable for Daily Use Yes Yes Yes
Invasiveness Non-invasive Non-invasive Non-invasive
Synergy Often combined with Hexapeptides or Matrixyl® Often combined with Octapeptides or Matrixyl® Often combined with Hexapeptides

 

 

FAQ - Acetyl Octapeptide-3 powder

Q: What is Acetyl Octapeptide-3 used for?
A: It is used in anti-aging skincare to reduce the appearance of expression lines by relaxing micro muscle contractions beneath the skin.

 

Q: Is Acetyl Octapeptide-3 the same as Argireline®?
A: No. Argireline® is Acetyl Hexapeptide-8 (hexapeptide), while Acetyl Octapeptide-3 (SNAP-8®) is an octapeptide with enhanced wrinkle-reducing potential.

 

Q: How is it applied?
A: Commonly used in creams, serums, and eye products at low concentrations (0.002%–0.05%) for optimal effect.

 

Q: Is it safe for daily use?
A: Yes. It is a topical cosmetic ingredient with a strong safety profile, mild, and reversible.

 

Q: Can it be combined with other peptides?
A: Yes. It is often used synergistically with Acetyl Hexapeptide-8, Matrixyl®, or other anti-aging peptides for multi-pathway benefits.

 

Where to find Chinese manufacture of Acetyl Octapeptide-3?

Choose novopept as your Acetyl Octapeptide-3 supplier.

  • Premium Quality – Cosmetic-grade SNAP-8® with consistent purity, tested by HPLC for reliable performance in anti-aging formulations.
  • Reliable Supply & Competitive Pricing – Flexible MOQs, stable production, and cost-efficient manufacturing from China.
  • Professional Support – Full documentation (COA, SDS) and technical guidance for formulation, regulatory compliance, and global shipment.

 

certifications

certifactions

 

 

Shipping methods

 

Shipping Terms 1

 

Country Delivery time 
Untied states  7-15 DAYS
Australia 7-12 DAYS
Germany 7-12 DAYS
Canada 8-10 DAYS
New zealand 7-10 DAYS
Uk 5-10 DAYS
Thailand 5-8 DAYS
Malaysia 5-8 DAYS
Vietnam 5-8 DAYS

 

The delivery time shown above is an estimate. Shipping routes and freight capacity may change from time to time. For the most accurate delivery schedule, please contact us directly.

 

Payment terms

 

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delivery records

 

tracking records

 

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Message us to get your personalized quotation within 24 hours.

 

  • Whatsapp:+852 6736 4057

  • Telegram:@hinovopept

  • Email:novopept@gmail.com

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Conclusion & Disclaimer

Acetyl Octapeptide-3 (CAS 868844-74-0) is a premium skincare peptide that helps smooth wrinkles, relax facial tension, and deliver visible anti-aging results - without injections. Safe, effective, and versatile, it's a go-to ingredient in modern anti-aging skincare formulations.
⚠️ Disclaimer: This page is for cosmetic and educational purposes only. Acetyl Octapeptide-3 is not FDA-approved as a drug or injectable treatment.

 

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