
Nad+ CAS 53-84-9
NAD+ is a powerhouse anti-aging molecule at the heart of modern cosmeceuticals. As skin ages, NAD+ levels decline — restoring them means restoring youthful energy, radiance, and resilience.
what's NAD+ (Nicotinamide Adenine Dinucleotide) CAS 53-84-9?
NAD+ (Nicotinamide Adenine Dinucleotide) is a critical coenzyme found in every living cell. It plays a central role in cellular energy metabolism, helping to convert food into energy and regulate key biological functions like DNA repair and cell survival. As we age, NAD+ levels naturally decline, which has been associated with numerous age-related health issues. This has led to increasing interest in NAD+ supplementation as a potential way to enhance vitality, support cellular health, and combat aging.
Novopept is a trusted NAD+ factory and professional supplier of Nicotinamide Adenine Dinucleotide (NAD+) (CAS No. 53-84-9) raw powder. We offer ≥99% purity with COA for every batch.
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| Parameter | Value |
|---|---|
| Chemical Name | Nicotinamide Adenine Dinucleotide (NAD+) |
| CAS Number | 53-84-9 |
| Molecular Formula | C21H27N7O14P2 |
| Molecular Weight | 663.5 g/mol |
| Purity | ≥ 98% (HPLC) |
| Appearance | White to off-white powder |
| Solubility | Soluble in water and alcohol |
| Storage Conditions | Store in a cool, dry place, away from light |
| Half-Life | Approximately 1-2 hours in human cells |
| Administration | Oral supplements, intravenous injections (clinical use) |
| Recommended Dosage | Typically 250-500 mg per day (for supplementation) |
| Shelf Life | 2 years when stored properly |
Benefits of NAD+
1. Cellular Energy Production
NAD+ is essential for converting food into cellular energy through its involvement in redox reactions in the mitochondria. By supporting cellular energy, NAD+ enhances overall vitality and stamina.
2. Anti-Aging Properties
NAD+ is integral in activating sirtuins, proteins that regulate cellular processes such as DNA repair, inflammation reduction, and gene expression. Higher NAD+ levels are linked to improved age-related health and longevity.
3. DNA Repair and Maintenance
As a coenzyme for the PARP (Poly (ADP-ribose) polymerase) enzymes, NAD+ helps repair damaged DNA. This is particularly important for maintaining the integrity of genetic material as cells age, reducing the risk of mutations and disease.
4. Cognitive Function
NAD+ supports brain health by maintaining mitochondrial function and energy in neurons. It has been linked to improved cognitive function, neuroprotection, and the reduction of age-related cognitive decline, including in conditions like Alzheimer's.
5. Metabolic Health
NAD+ influences key metabolic pathways, including glucose metabolism and fat oxidation. It may also help improve insulin sensitivity, making it valuable for weight management and reducing the risk of metabolic disorders.
6. Improved Muscle Function and Recovery
NAD+ enhances the function of mitochondria, which are essential for muscle performance and recovery. It has been shown to improve muscle endurance and recovery time in athletes and individuals undergoing physical rehabilitation.
7. Immune System Support
NAD+ is involved in immune response regulation, helping to maintain optimal immune function and supporting the body's defense against pathogens and infections.
Mechanism of Action
1. Cellular Energy Production
NAD+ is essential for the electron transport chain (ETC) in mitochondria, where it helps convert nutrients into ATP (energy). NAD+ is reduced to NADH, donating electrons to produce ATP, maintaining energy levels in cells.
Effect: Supports cellular energy production and overall vitality.
2. DNA Repair
NAD+ activates PARPs (DNA repair enzymes) that use it to repair damaged DNA, maintaining genomic stability and reducing mutations.
Effect: Enhances DNA repair and promotes anti-aging.
3. Sirtuin Activation
NAD+ activates sirtuins, proteins that regulate gene expression, cell survival, and stress response, which are key for longevity and cellular resilience.
Effect: Supports longevity, anti-inflammatory effects, and cell survival.
4. Metabolic Regulation
NAD+ promotes fat oxidation and regulates insulin sensitivity, improving metabolism and supporting weight management.
Effect: Enhances fat burning and metabolic health.
5. Cognitive Function
NAD+ helps maintain mitochondrial function in neurons, supporting brain health and neuroprotection against age-related cognitive decline.
Effect: Supports cognitive function and neuroprotection.
Conclusion
NAD+ is crucial for energy production, DNA repair, metabolic health, and brain function, making it a key molecule in anti-aging and wellness.
Side Effects of NAD+
Headaches
Some individuals may experience headaches, particularly when starting supplementation.
Fatigue or Dizziness
In rare cases, NAD+ supplementation may cause feelings of fatigue or lightheadedness, especially if taken in high doses.
Nausea
Some people may experience mild nausea, particularly when taking NAD+ on an empty stomach.
Flushing or Warmth
A mild flushing or a sensation of warmth in the skin can occur, especially if NAD+ is administered intravenously.
Digestive Discomfort
Some users may experience gas, bloating, or mild gastrointestinal discomfort when taking NAD+ orally.
Increased Heart Rate
In rare cases, NAD+ may lead to a slight increase in heart rate or palpitations.

Comparison: NAD+ vs. NADH
| Characteristic | NAD+ | NADH |
|---|---|---|
| Primary Function | Energy production, DNA repair, anti-aging | Energy production, cognitive support |
| Best for | Cellular health, aging, metabolic support | Mental clarity, fatigue, cognitive function |
| Mechanism of Action | Supports cellular energy and sirtuin activation | Directly provides energy by reducing NAD+ to NADH |
| Supplement Form | Oral capsules, IV injections (clinical) | Oral tablets, sublingual forms |
FAQ
1. What is NAD+?
NAD+ (Nicotinamide Adenine Dinucleotide) is a crucial coenzyme found in all living cells, vital for energy metabolism and DNA repair. It plays a significant role in cellular energy production and anti-aging processes.
2. How does NAD+ benefit the body?
NAD+ promotes energy production, DNA repair, cell regeneration, and activates sirtuins, proteins that regulate aging processes. Supplementing NAD+ can help combat the effects of aging and support cognitive and metabolic health.
3. How is NAD+ taken?
NAD+ is typically taken in the form of oral supplements or intravenous (IV) injections under medical supervision. The recommended dosage is usually 250-500 mg per day.
4. Is NAD+ safe to use?
Yes, NAD+ supplementation is generally considered safe when used appropriately. However, it is always advised to consult with a healthcare professional before starting any new supplement regimen, especially for those with underlying health conditions.
5. Can NAD+ help with weight loss?
NAD+ plays a role in metabolism regulation and fat oxidation, potentially supporting weight loss efforts. It enhances insulin sensitivity and helps regulate glucose metabolism, making it beneficial for metabolic health.
6. What's the difference between NAD+ and NADH?
NAD+ is the oxidized form that helps in energy production and DNA repair, while NADH is the reduced form, directly involved in boosting energy and mental clarity. Both are essential, but they serve different purposes in the body.
7. Can NAD+ improve mental clarity?
Yes, NAD+ supports brain health and cognitive function by maintaining mitochondrial function in neurons, which can result in improved focus and mental clarity over time.
Why Choose us?
High Purity: Our NAD+ is guaranteed to be of the highest quality with a purity of ≥ 98%
Scientific Backing: NAD+ supplementation has been widely researched for its potential to support longevity, cellular health, and metabolic function.
Efficient Delivery: Our NAD+ is optimized for maximum absorption and bioavailability, ensuring your body gets the full benefits.
Trusted Manufacturer: We are a leading supplier of premium-quality NAD+ for research purposes, providing you with reliable and effective products.
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| Country | Delivery time |
| Untied states | 7-15 DAYS |
| Australia | 7-12 DAYS |
| Germany | 7-12 DAYS |
| Canada | 8-10 DAYS |
| New zealand | 7-10 DAYS |
| Uk | 5-10 DAYS |
| Thailand | 5-8 DAYS |
| Malaysia | 5-8 DAYS |
| Vietnam | 5-8 DAYS |
The delivery time shown above is an estimate. Shipping routes and freight capacity may change from time to time. For the most accurate delivery schedule, please contact us directly.
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Conclusion
NAD+ (CAS 53-84-9) is a vital coenzyme in the body, supporting a wide range of functions from energy metabolism to DNA repair and anti-aging processes. Supplementing NAD+ can significantly enhance cellular health, improve cognitive function, support metabolic health, and promote longevity. With its growing popularity in anti-aging and wellness circles, NAD+ offers promising benefits for those looking to improve overall vitality and health.
For more information or to place an order, contact us today and start your journey toward better health with NAD+!
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