KPV CAS 67727-97-3
KPV peptide CAS 67727-97-3 is a naturally derived tripeptide (Lys-Pro-Val) and fragment of alpha-MSH (melanocyte-stimulating hormone). It has gained attention for its anti-inflammatory, healing, and immune-modulating properties. Research suggests that KPV may support gut health, skin repair, and immune balance, making it a promising candidate in cosmetic, dermatological, and inflammation-related studies.
what's KPV peptide CAS 67727-97-3?
KPV peptide CAS 67727-97-3 is a naturally derived tripeptide (Lys-Pro-Val) and fragment of alpha-MSH (melanocyte-stimulating hormone). It has gained attention for its anti-inflammatory, healing, and immune-modulating properties. Research suggests that KPV may support gut health, skin repair, and immune balance, making it a promising candidate in cosmetic, dermatological, and inflammation-related studies.
Technical Data
| Parameter | Specification |
|---|---|
| KPV CAS Number | 67727-97-3 |
| Molecular Formula | C₁₆H₂₉N₅O₄ |
| Molecular Weight | ~359.4 g/mol |
| Amino Acid Sequence | Lys–Pro–Val |
| Appearance | White to off-white lyophilized powder |
| Purity | ≥98% (HPLC) |
| Identification | HPLC, MS |
| Solubility | Soluble in water or aqueous buffers |
| Storage | −20 °C, dry and protected from light |
| Stability | Stable for ≥24 months when stored properly |
KPV Research & Applications
• Anti-Inflammatory:
Suppresses NF-κB activation, reducing pro-inflammatory cytokines in intestinal and immune cells.
01
• Gut & Autoimmune Health:
Studied in colitis and IBD models where it reduced inflammation and supported mucosal healing.
02
• Skin & Cosmetic Uses:
Marketed in some formulations as an anti-wrinkle and skin-healing peptide.
03
• Immune Modulation:
Reported to balance overactive immune responses in mast cell activation syndrome (MCAS) and inflammation-linked disorders.
04
• Combination Protocols:
Often stacked with BPC-157, TB-500, or GHK-Cu for enhanced healing or skin rejuvenation.
05
KPV Side Effects
• Skin rashes, itching, or worsening irritation in some cases.
• Occasional fatigue, tingling, or nerve-like discomfort (often in combination protocols).
• No long-term safety data; considered an experimental research peptide.
Comparison: KPV vs BPC-157 vs TB-500
|
Feature |
KPV |
BPC-157 |
TB-500 (Thymosin Beta-4 fragment) |
|
CAS Number |
67727-97-3 |
137525-51-0 |
77591-33-4 |
|
Type |
Tripeptide (Lys-Pro-Val, α-MSH fragment) |
15-AA peptide from Body Protection Compound |
Peptide fragment of Thymosin Beta-4 |
|
Main Actions |
Anti-inflammatory, immune modulation, skin/gut health |
Angiogenesis, tendon/ligament healing, gut protection |
Cell migration, wound repair, tissue regeneration |
|
Research Areas |
MCAS, IBD, colitis, skin repair, long COVID |
GI healing, musculoskeletal injuries, neuroprotection |
Wound healing, heart repair, eye injuries, tissue regeneration |
|
User Reports |
Reduces inflammation, may cause skin rashes in some cases |
Improved recovery, gut healing, occasional dizziness/nausea |
Better wound closure, faster recovery, mild fatigue |
|
Approval Status |
Research only, not FDA-approved |
Research only, not FDA-approved |
Research only, not FDA-approved |
- KPV is best suited for anti-inflammatory and immune modulation research, offering a simple structure and cost-effective synthesis.
- BPC-157 is a versatile peptide widely studied in tissue protection, gastrointestinal, and vascular research.
- TB-500 (Thymosin Beta-4 fragment) is primarily associated with cell migration, angiogenesis, and musculoskeletal regeneration studies, though it involves higher synthesis complexity.
When to Choose KPV vs BPC-157 vs TB-500
- - Choose KPV if inflammation control is the priority.
- - Choose BPC-157 if you want to support recovery from injuries or gut healing.
- - Choose TB-500 if systemic tissue regeneration or wound healing is the goal.
FAQ - KPV Peptide
**Q1: What is KPV used for?**
Research suggests anti-inflammatory, gut-healing, and skin-repair properties. Some forums discuss use in long COVID, MCAS, and mold-related issues.
**Q2: Does KPV promote muscle growth or hormones?**
No. Unlike many peptides, KPV is not anabolic. Its focus is on immune balance and inflammation control.
**Q3: What side effects do people mention?**
Skin rashes, itching, and rare systemic symptoms like fatigue or tingling. Most describe it as mild but emphasize lack of long-term data.
**Q4: How do people use it in stacks?**
Commonly combined with BPC-157 (healing), GHK-Cu (skin/cosmetic), or TB-500 (repair).
**Q5: Is KPV safe for humans?**
It is not FDA-approved and remains a research chemical. Use is limited to experimental and laboratory settings.
Why Choose a Professional KPV Manufacturer or China Supplier?
- Advanced solid-phase peptide synthesis (SPPS) technology
- Strict QC including HPLC and mass spectrometry
- Flexible batch sizes from milligram to gram scale
- KPV COA and technical documentation available
- Competitive KPV pricing and reliable global supply
Shipping methods
| Country | Delivery time |
| Untied states | 7-15 DAYS |
| Australia | 7-12 DAYS |
| Germany | 7-12 DAYS |
| Canada | 8-10 DAYS |
| New zealand | 7-10 DAYS |
| Uk | 5-10 DAYS |
| Thailand | 5-8 DAYS |
| Malaysia | 5-8 DAYS |
| Vietnam | 5-8 DAYS |
The delivery time shown above is an estimate. Shipping routes and freight capacity may change from time to time. For the most accurate delivery schedule, please contact us directly.
Payment terms
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